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SELL Gene - GeneCards | LYAM1 Protein | LYAM1 Antibody
genecards.org/cgi-bin/carddisp.pl?gene=Sell

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Description:
Complete information for SELL gene (Protein Coding), Selectin L, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium

Keywords:
SELL, SELL gene, LYAM1 protein, LYAM1 antibody, Selectin L, Leukocyte-Endothelial Cell Adhesion Molecule 1, CD62 Antigen-Like Family Member L, Leukocyte Surface Antigen Leu-8, Lymphocyte Adhesion Molecule 1, Lymph Node Homing Receptor, Gp90-MEL, LECAM1, LYAM1, LNHR, TQ1, Leukocyte Adhesion Molecule 1, Pln Homing Receptor, CD62L Antigen, L-Selectin, CD62L, PLNHR, LAM-1, LAM1, LEU8, LSEL

Keywords (tags)

adhesion antibodies antibody binding cell ensembl gene genes p14151 phenotype products protein proteins selectin sell

Content Summary

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing re... The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth fact... The gene product is required for binding and subsequent rolling of leucocytes on endothelial cell... Single-nucleotide polymorphisms in this gene have been associated with various diseases including... Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct... GeneCards Summary for SELL Gene SELL (Selectin L) is a Protein Coding gene. Protein attributes for SELL Gene Size: 372 amino acids Molecular mass: 42187 Da Quaternary structure: Interaction with PSGL1/SELPLG and PODXL2 is required for promoting recruitment and rolling of leu... This interaction is dependent on the sialyl Lewis X glycan modification of PSGL1 and PODXL2, and ... Sulfation on Tyr-51 of PSGL1 is important for L-selectin binding. SequenceCaution: Sequence=CAA3420... Molecular function for SELL Gene GENATLAS Biochemistry: L selectin,leukocyte adhesion molecule,74kDa,co... expressed on monocytes,... SELL UniProtKB/Swiss-Prot Function: Cell surface adhesion protein. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in periphe... Promotes initial tethering and rolling of leukocytes in endothelia. LYAM1_HUMAN,P14151

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